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Cayman Chemical A803467 Ion Channel Modulators
Supplier: Cayman Chemical 1001258850 MG
A sodium channel blocker with high-affinity and selectivity for inhibiting human Nav1.8 sodium channels (IC50 = 8 nM when stimulated at half-maximal inactivation and IC50 = 79 nM at a resting state); dose dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models
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