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ABclonal Technology RAIDD/CRADD Rabbit mAb
SDP

Supplier:  ABclonal Technology A8663500UL

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This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.

Catalog No. 50-001-34860


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