Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ABclonal Technology A8953-500ul Neutrophil Elastas
Supplier: ABclonal Technology A8953500UL
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin Humans have six elastase genes which encode structurally similar proteins The encoded preproprotein is proteolytically processed to generate the active protease Following activation this protease hydrolyzes proteins within specialized neutrophil lysosomes called azurophil granules as well as proteins of the extracellular matrix The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin This protein also degrades the outer membrane protein A (OmpA) of E coli as well as the virulence factors of such bacteria as Shigella Salmonella and Yersinia Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN) This gene is present in a gene cluster on chromosome 19
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction