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Cayman Chemical A943931hydroCLOrID hydra 10mg
SDP

Supplier:  Cayman Chemical 3455410 MG

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An irreversible inhibitor of TrxR1 (IC50 0.012 UM) inhibits TrxR1-induced reduction of Trx1 in a cell-free assay (IC50 4.3 UM) reduces the mitochondrial oxygen consumption rate in HCT116 cells at 10 UM increases the intracellular levels of hydrogen peroxide in FaDu cancer cells in a time- and concentration-dependent manner decreases the viability of FaDu cells (IC50 0.72 UM) decreases tumor growth in a FaDu HNSCC mouse xenograft model at 10 mg/kg twice per day induces apoptosis in a FaDu HNSCC mouse xenograft model at 5 mg/kg daily toxic to S. mansoni adult worms (LD50 10.07 UM)

Catalog No. 50-294-7466


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