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Medchemexpress LLC AA-T3A-C12 | 2938207-23-7 | 99.8% | 1059.72 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14885950MG

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AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid) known for facilitating significant RNA delivery and transfection in activated fibroblasts. It enhances uptake of siRNA LNP by TGF-β-stimulated 3T3 fibroblasts and enables robust gene knockdown in in vitro studies. In vivo research shows AA-T3A-C12/siHSP47 LNP can significantly down-regulate HSP47 expression in fibrotic mice.

  • Anisamide ligand-tethered lipidoid (AA-lipidoid).
  • Mediates great RNA delivery.
  • Facilitates transfection of activated fibroblasts.
  • Enhances uptake of siRNA LNP by TGF-β-stimulated 3T3 fibroblasts.
  • Enables robust gene knockdown in activated fibroblasts.
  • Significantly down-regulates HSP47 expression in fibrotic mice when used as AA-T3A-C12/siHSP47 LNP.

Catalog No. 50-003-59854


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