Medchemexpress LLC Ab-680 | 2105904-82-1 | 99.7% | 580.82 | C20H24ClFN4O9P2 | 10MG

Supplier:  Medchemexpress LLC HY12528610MG

AB-680 is a potent, reversible, and selective small-molecule inhibitor of CD73 developed for cancer immunotherapy research. It inhibits human CD73 with picomolar potency, demonstrates strong selectivity over related ecto-nucleotidases, and has shown antitumor activity in preclinical models.

• Potent, reversible inhibitor of CD73 with picomolar potency.
• Greater than 10,000-fold selectivity over related ecto-nucleotidases.
• High chemical purity and enantiomeric excess for reproducible results.
• Soluble in DMSO at 100 mg/mL and in water at 5 mg/mL with warming.
• Stable as a powder when stored at -20°C under inert gas.
• Stable in solution when stored at -80°C for long-term use.
• Suitable for biochemical assays, cellular studies, and preclinical pharmacology.

Catalog No. 50-002-35671