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Apexbio Technology LLC Abacavir sulfate 188062-50-2 10mg
Supplier: Apexbio Technology LLC B222010
Abacavir sulfate (188062-50-2) is a small-molecule inhibitor targeting HIV reverse transcriptase It is designed to inhibit reverse transcriptase activity thereby blocking viral DNA synthesis Abacavir sulfate exerts its biological activity primarily through intracellular conversion to its active triphosphate form which competes with endogenous substrates to terminate viral nucleic acid polymerization In cell-based studies Abacavir sulfate demonstrates inhibitory activity with an IC50 range of 1 2 to 6 2 M depending on the cell line and experimental protocol Based on these pharmacological properties Abacavir sulfate holds research potential in antiviral research particularly for in vitro HIV infection assays and resistance pathway analyses
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