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ABclonal Technology ABCA1 Rabbit mAb
SDP

Supplier:  ABclonal Technology A2212520UL

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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters ABC proteins transport various molecules across extra- and intracellular membranes ABC genes are divided into seven distinct subfamilies (ABC1 MDR TAP MRP ALD OABP GCN20 White) This protein is a member of the ABC1 subfamily Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes With cholesterol as its substrate this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency

Catalog No. 50-000-07602


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