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ABclonal Technology ABflo 647 Rabbit anti- IgE
Supplier: ABclonal Technology A24275200T
Immunoglobulins (antibodies) are glycoproteins produced by B lymphocytes and play key roles in humoral immunity The constant region of the immunoglobulin heavy chains is essential for their function Membrane-bound immunoglobulins act as receptors on B cells triggering clonal expansion and differentiation into plasma cells upon antigen binding Secreted immunoglobulins eliminate bound antigens during the effector phase The antigen-binding site is formed by the variable domains of a heavy and light chain with two binding sites on each immunoglobulin These variable domains are generated through V-(D)-J rearrangement and can undergo somatic hypermutation enabling affinity maturation for specific antigens after exposure and selection
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