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Cayman Chemical Abrocitinib 10mg
SDP

Supplier:  Cayman Chemical 3486910 MG

Encompass_Preferred

A JAK1 inhibitor (IC50 = 0.029 µM); selective for JAK1 over JAK2, JAK3, and TYK2 (IC50s = 0.803, >10, and 1.253 µM, respectively) and a panel of 40 kinases at 1 µM; inhibits IFN-α-, IL-21-, or IL-27-induced phosphorylation of STAT3 (IC50s = 0.189, 0.511, and 0.271 µM, respectively) and IFN-γ-induced phosphorylation of STAT1 (IC50 = 0.163 µM) in isolated human whole blood; reduces paw edema in a rat model of adjuvant-induced arthritis at 1, 5, and 15 mg/kg

Catalog No. 50-291-0311


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