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Enzo Life Sciences Ac-DEVD-CHO (1mg). CAS: 169332-60-9
Supplier: Enzo Life Sciences ALX260030M001
Caspase-3 inhibitor. Highly specific, potent and reversible inhibitor of caspase-3. Ki<1nM for purified caspase-3. IC50=0.2nM for PARP cleavage in cultured human osteosarcoma cell extracts. In contrast, the caspase-1 (ICE) specific inhibitor YVAD-CHO has a Ki=12µM for caspase-3 and IC50>10µM for PARP cleavage in osteosarcoma cell extracts. The DEVD sequence is based on PARP cleavage site Asp-216 for caspase-3. Alternative name: Caspase-3 inhibitor (aldehyde), Caspase-7 inhibitor (aldehyde). Formula: C20H30N4O11. MW: 502.5. Purity: ≥95% (HPLC). Formulation: Lyophilized. Peptide content: 70-90%. Solubility: Soluble in distilled water or DMSO. Long Term Storage: -20°C. Use/Stability: Stock solutions should be divided into aliquots and stored at -20°C. Solutions are stable for at least 1 month when stored at -20°C in the dark and protected from moisture. Handling: Keep under nitrogen. Keep cool and dry.
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