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Ubpbio A fluorogenic substrate of the branched amino acid preferring activity of proteasomes. Preferentially cleaved by immunoproteasomes.
Supplier: Ubpbio G2110
Ac-PAL-AMC is a fluorogenic substrate of the caspase-like activity of the proteasome. It is preferentially cleaved by immunoproteasomes compared to constitutive proteasomes. The AMC fluorescence can be detected by a fluorimeter or a plate reader using excitation/emission wavelengths at 360 nm/460 nm, respectively. This substrate can be used to determine the caspase-like activity of immunoproteasomes. Working concentration is 50 - 200 µM.
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