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CPC Scientific Ac-Trp-Glu-His-Asp-AMC (trifluoroacetate salt) 1MG

Supplier: CPC Scientific CASP003A

With a Kcat/Km of 3.3 x 106 M-1s-1 this fluorogenic caspase-1 substrate is cleaved 50-fold more efficiently than CASP-010. This phenomena shows that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.SEQUENCE: Ac-Trp-Glu-His-Asp-AMC (trifluoroacetate salt)ONE-LETTER SEQUENCE: Ac-WEHD-AMCMOLECULAR FORMULA: C38H40N8O11MOLECULAR WEIGHT: 784.8STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [189275-74-9]SYNONYMS: RESEARCH AREA: ApoptosisREFERENCES:T.A. Rano et al., Chem. Biol. 4, 149 (1997)SKU(s): CASP-003A
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