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Medchemexpress LLC Ac2-26 | 151988-33-9 | 99.43% | 3089.43 | 10 MG

Supplier: Medchemexpress LLC HYP109810MG
Ac2-26 is the N-terminal peptide of annexin 1, exhibiting anti-inflammatory activity. It acts by decreasing IKKβ protein in lysosomes through chaperone-mediated autophagy (CMA), ameliorating lung ischemia-reperfusion injury, and inhibiting airway inflammation and hyperresponsiveness in an asthma rat model.
- Exhibits anti-inflammatory activity
- Decreases IKKβ protein via chaperone-mediated autophagy
- Ameliorates lung ischemia-reperfusion injury
- Inhibits airway inflammation and hyperresponsiveness
- Inhibits inflammatory cytokines and apoptosis in LPS-induced HK-2 cells
- Increases rat cardiomyocyte rFprs expression and prevents cell injury
- Reduces cardiac necrosis and inflammation in I-R injury model
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