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Medchemexpress LLC Ac2-26 | 151988-33-9 | 99.43% | 3089.43 | 10 MG
SDP

Supplier:  Medchemexpress LLC HYP109810MG

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Ac2-26 is the N-terminal peptide of annexin 1, exhibiting anti-inflammatory activity. It acts by decreasing IKKβ protein in lysosomes through chaperone-mediated autophagy (CMA), ameliorating lung ischemia-reperfusion injury, and inhibiting airway inflammation and hyperresponsiveness in an asthma rat model.

  • Exhibits anti-inflammatory activity
  • Decreases IKKβ protein via chaperone-mediated autophagy
  • Ameliorates lung ischemia-reperfusion injury
  • Inhibits airway inflammation and hyperresponsiveness
  • Inhibits inflammatory cytokines and apoptosis in LPS-induced HK-2 cells
  • Increases rat cardiomyocyte rFprs expression and prevents cell injury
  • Reduces cardiac necrosis and inflammation in I-R injury model

Catalog No. 50-004-24137


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