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Medchemexpress LLC Acalisib | 870281-34-8 | 99.98% | 401.40 | 100MG
Supplier: Medchemexpress LLC HY12644100MG
Acalisib is a potent and selective PI3Kδ inhibitor with an IC50 of 12.7 nM. It is for research use only and not sold to patients.
- More selective for PI3Kδ (IC50=12.7 nM) compared to other PI3K class I enzymes.
- Reduces PDGF-induced pAkt by 50% at 11,585 nM and LPA-induced pAkt by 50% at 2,069 nM in fibroblasts.
- Sufficient to reduce the growth of multiple myeloma xenografts in mice.
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