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AdipoGen ACBP human ELISA Kit
Supplier: AdipoGen AG45B0019KI01
Colorimetric Sandwich ELISA Assay. Detects human ACBP in serum, plasma and cell culture supernatant. Range 0.03125 to 2ng/ml. Sensitivity 26pg/ml. Acyl-coenzyme A CoA-binding protein ACBP is an ubiquitously expressed 86 aa polypeptide that binds medium- and long-chain acyl-CoA esters with very high affinity. It plays a role as an intracellular carrier of acyl-CoA esters and regulates lipid metabolism in the cytoplasm of most cell types. In addition to its function within the cells as acyl-coenzyme A CoA-binding protein, ACBP also functions as secreted protein called Diazepam-Binding Inhibitor DBI that can interact with the benzodiazepine-binding site of the gamma-aminobutyric acid GABA type A receptor, GABAAR, and modulate its activity. ACBP is secreted upon induction of autophagy energy deficiency in different organisms including mouse and human. ACBP levels correlate with human body mass index BMI.
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