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ABclonal Technology ACE1 Rabbit mAb
SDP

Supplier:  ABclonal Technology A2581520UL

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This gene encodes an enzyme that regulates blood pressure and electrolyte balance by converting angiotensin I into angiotensin II a potent vasopressor and aldosterone-stimulating peptide Angiotensin II controls blood pressure and fluid balance while the enzyme also inactivates the vasodilator bradykinin As a target of ACE inhibitors it is used to treat high blood pressure The enzyme also influences fertility by cleaving GPI-anchored membrane proteins in sperm A 287 bp Alu repeat polymorphism in this gene is linked to enzyme levels with mutations associated with cardiovascular diseases psoriasis renal disease stroke and Alzheimer s The homologous ACE2 gene plays a role in diseases caused by human coronaviruses including SARS-CoV and SARS-CoV-2 Alternative splicing generates somatic (sACE) and male-specific testicular (tACE) isoforms

Catalog No. 50-000-09141


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