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Medchemexpress LLC Acebilustat | 943764-99-6 | 99.7% | 481.54 | 100 MG
Supplier: Medchemexpress LLC HY17625100MG
Acebilustat is a leukotriene A4 hydrolase inhibitor, used as an oral antiinflammatory agent. It is safe and well tolerated in phase 1 trials. This antiinflammatory drug is in development for the treatment of CF and other diseases, acting as a potent inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H), which catalyzes the rate-limiting step in the formation of leukotriene B4 (LTB4), a powerful chemoattractant and activator of inflammatory immune cells like neutrophils.
- Leukotriene A4 hydrolase inhibitor
- Oral antiinflammatory agent
- Safe and well tolerated in phase 1 trials
- Potent inhibitor of LTA4H
- Inhibits the formation of leukotriene B4 (LTB4)
- Being developed for the treatment of cystic fibrosis (CF) and other diseases
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