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Medchemexpress LLC Acetamide, N-[(1S)-2-[(3E,5E)-3,5-bis(4-nitrophenyl)methylene]-4-oxo-1-piperidinyl]-2-chloro- | 2649154-57-2 | 99.9% | C30H25ClN4O7 | 10MG
SDP

Supplier:  Medchemexpress LLC HY13656310MG

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RA375 is a small-molecule inhibitor of RPN13, a regulatory subunit of the 26S proteasome. It activates unfolded protein response signaling, increases reactive oxygen species production, and induces apoptosis in cancer cell lines; it has shown in vivo efficacy reducing ovarian tumor burden in mice. Intended for research use only.

  • Potent RPN13 inhibitor with cellular activity.
  • Activates unfolded protein response and increases ROS production.
  • Induces apoptosis in cancer cell lines.
  • Demonstrated in vivo tumor reduction at reported dosing.
  • Light yellow to yellow solid with defined storage conditions.
  • High purity suitable for research applications.

Catalog No. 50-002-59871


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