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Medchemexpress LLC Acetamide, N-ethyl-2-[(6-methoxy-3-pyridinyl) [(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)- | 680590-49-2 | 99.9% | 454.54 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY10868250MG

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EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. It binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively. EMPA competitively antagonizes orexin-A-and orexin-B-evoked accumulation of [3H]inositol phosphates (IP) at hOX2 receptors. It displaces [3H]EMPA binding from cell membranes containing human and rat OX2 receptors.

  • High-affinity, reversible and selective orexin OX2 receptor antagonist
  • Binds to human and rat OX2-HEK293 membranes
  • Inhibits orexin-A-or orexin-B-evoked [Ca2+]i response

Catalog No. 50-003-46364


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