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Medchemexpress LLC Acetylene-linker-Val-Cit-PABC-MMAE | 1411977-95-1 | 95.2% | 1307.62 g/mol | C67H106N10O16 | 10 MG
Supplier: Medchemexpress LLC HY1981210MG
Acetylene-linker-Val-Cit-PABC-MMAE is an antibody-drug conjugate (ADC) linker-payload conjugate that couples an alkyne-bearing cleavable Val-Cit-PABC linker to the tubulin inhibitor MMAE. The acetylene handle enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation, while the Val-Cit-PABC motif permits proteolytic release of the payload after internalization.
- Contains an alkyne handle for CuAAC click chemistry
- Val-Cit-PABC motif enables proteolytic release of MMAE
- Provides a cleavable linker-payload architecture for ADC development
- Molecular formula C67H106N10O16 and molecular weight 1307.62 g/mol
- Typical purity approximately 95.2%
- Supplied as a 10 mg sample; store at 4°C under inert atmosphere
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