Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Acp-5862 | 2230757-47-6 | 98.3% | C26H23N7O3 | 10MG
Supplier: Medchemexpress LLC HY13533410MG
ACP-5862 is the major active, circulating, pyrrolidine ring-opened metabolite of acalabrutinib that inhibits Bruton tyrosine kinase (BTK). It has been characterized for its contribution to acalabrutinib's pharmacological activity and displays potent BTK inhibition alongside weak, time-dependent inactivation of select cytochrome P450 enzymes. Supplied for research use with supporting analytical documentation.
- Potent BTK inhibition (IC50 ≈ 5.0 nM).
- Major circulating metabolite of acalabrutinib.
- Weak time-dependent inactivator of CYP3A4 and CYP2C8.
- Available as solid and as a DMSO solution.
- High analytical purity (~98.3% by HPLC).
- Supplied with certificate of analysis and safety data sheet.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?