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Medchemexpress LLC Acy-775 | 1375466-18-4 | 99.7% | 330.36 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY19328100MG

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ACY-775 is a potent and selective inhibitor of histone deacetylase 6 (HDAC6) with an IC50 of 7.5 nM. It also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2). Treatment with ACY-775 enhances the acetylation of α-tubulin, while histone acetylation remains unaltered.

  • Potent and selective inhibitor of HDAC6
  • Enhances acetylation of α-tubulin
  • Increases motility and total number of mitochondria within neurites in DRG neurons
  • Rapid elimination from plasma (half-life of 12 min)

Catalog No. 50-003-85792


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