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Medchemexpress LLC Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] | 136834-22-5 | 99.4% | 875.92 | 1 G
SDP

Supplier:  Medchemexpress LLC HY219971G

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DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides. These oligonucleotides are characterized by high nuclease resistance, strong RNA binding affinity, and maintained base-pair specificity. The 2'-fluoro modification enhances the stability of the hybrid duplex and promotes an A-form conformation.

  • Enhances stability of hybrid duplex
  • Promotes an A-form conformation
  • Used for synthesizing antisense oligonucleotides
  • Provides high nuclease resistance
  • Offers strong RNA binding affinity
  • Maintains base-pair specificity

Catalog No. 50-004-00815


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