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Medchemexpress LLC Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] | 136834-22-5 | 99.4% | 875.92 | 250 MG
SDP

Supplier:  Medchemexpress LLC 250MGHY21997

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DMT-2'fluoro-da(bz) amidite is a crucial intermediate used in the synthesis of antisense oligonucleotides. These oligonucleotides are known for their high resistance to nucleases, strong RNA binding affinity, and maintained base-pair specificity.

  • Key intermediate for synthesizing antisense oligonucleotides.
  • Antisense oligonucleotides exhibit high nuclease resistance.
  • Antisense oligonucleotides possess high RNA binding affinity.
  • Antisense oligonucleotides maintain base-pair specificity.
  • The 2'-fluoro modification enhances the stability of hybrid duplex.
  • The 2'-fluoro modification makes the duplex present an A-form conformation.

Catalog No. 50-004-02240


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