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AdipoGen AEBSF hydrochloride

Supplier: AdipoGen AGCR13610M050
Chemical. CAS 30827-99-7. Formula C8H10FNO2S . HCl. MW 203.2 . 36.5. Synthetic. Water soluble, irreversible serine protease chymotrypsin, kallikrein, plasmin, thrombin and trypsin inhibitor. Stable, non-toxic alternative to PMSF. Potent, selective inhibitor of Site-1-protease S1P. Used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation by selectively inhibiting S1P. NADPH oxidase inhibitor. Inhibits activation of TGFbeta and activates JNK and p38 MAP kinases. beta-Secretase inhibitor. Shown to inhibit beta-amyloid peptide production and enhance APP amyloid precursor protein secretion in several cell lines at millimolar concentrations.
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