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ABclonal Technology AER61 Rabbit mAb
SDP

Supplier:  ABclonal Technology A2116620UL

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This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains including the Notch receptor thereby regulating developmental signalling Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4 Alternative splicing results in multiple transcript variants

Catalog No. 50-000-07576


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