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Selleck Chemical LLC Agerafenib

Supplier: Selleck Chemical LLC S80155MG
Agerafenib (CEP-32496) is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM also potent to Abl-1 c-Kit Ret (c-Ret) PDGFR and VEGFR2 respectively insignificant affinity for MEK-1 MEK-2 ERK-1 and ERK-2 Phase 1/2
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