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Medchemexpress LLC AGX51 | 330834-54-3 | 99.3% | 431.52 | 5 MG
Supplier: Medchemexpress LLC 5MGHY129241
AGX51 is a first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader, primarily used in cancer research. It functions by inhibiting Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids. This action results in cell growth arrest and a reduction in cell viability, demonstrating an ability to inhibit Triple-Negative Breast Cancer (TNBC) with an IC50 of approximately 25 nM.
- First-in-class pan-Id antagonist and degrader
- Inhibits Id1-E47 interaction
- Leads to ubiquitin-mediated degradation of Ids
- Results in cell growth arrest and viability reduction
- Effective in inhibiting Triple-Negative Breast Cancer (TNBC)
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