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Apexbio Technology LLC Alcaftadine 147084-10-4 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B35185.1
Alcaftadine (CAS 147084-10-4) is a small-molecule histamine H1 receptor antagonist that inhibits the actions of histamine thereby mitigating inflammatory responses By blocking H1 receptor activation on conjunctival cells it prevents downstream signaling events associated with allergic symptoms such as pruritus Alcaftadine is utilized as a pharmacological tool to study histamine-mediated pathways and allergic cascade mechanisms with particular relevance to ocular models of allergic conjunctivitis Its approval for clinical use underscores its selectivity for the H1 receptor and its utility in delineating histamine-driven immunological processes
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