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ABclonal Technology ALDH3A1 Rabbit mAb

Supplier: ABclonal Technology A23088100UL
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids biogenic amines neurotransmitters and lipid peroxidation The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea The gene is located within the Smith-Magenis syndrome region on chromosome 17 Multiple alternatively spliced variants encoding the same protein have been identified
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