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Enzo Life Sciences ALK5 Inhibitor II, (5mg), CAS Number: 446859-33-2
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Supplier:  Enzo Life Sciences ALX270445M005

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Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-β RI kinase (IC50=23nM, 4nM and 18nM for binding, auto-phosphorylation and cellular assay in HepG2 cells of TGF-β RI kinase, respectively). Minimally affects a panel of 9 closely related kinases including p38 MAPK (IC50>16µM). Alternative Name: TGF-beta RI Kinase Inhibitor II. 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine. Formula: C17H13N5. MW: 287.3. CAS Number: 446859-33-2. Purity: ≥97% (HPLC). Appearance: White to off-white or yellow solid. Solubility: 5mg/ml soluble in DMSO or methanol. Use/Stability: Stable for 2 years after receipt when stored at -20°C. Stock solutions are stable for up to 6 months when stored at -20°C. Long Term Storage: -20°C

Catalog No. NC1162509


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