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Medchemexpress LLC ALLO-2 | 1357350-60-7 | 99.7% | 371.32 g/mol | C18H12F3N5O | 1 ML
Supplier: Medchemexpress LLC HY11740710MM 1ML
ALLO-2 is a small-molecule Smoothened (Smo) mutant antagonist that inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with an IC50 of 6 nM. It is supplied for research use as solid material or as a pre-made 10 mM solution in DMSO (1 mL).
- Potent Smo mutant antagonist with IC50 ≈ 6 nM.
- Active against drug-resistant Smoothened mutants, suitable for pathway inhibition studies.
- Available as solid or as a pre-made 10 mM solution in DMSO for rapid in vitro use.
- High purity (99.7%), appropriate for research applications.
- Useful for luciferase reporter assays and other cell-based Smo activity assays.
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