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Medchemexpress LLC Alpelisib (hydrochloride) | 1584128-91-5 | C19H23ClF3N5O2S | 200 MG
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Supplier:  Medchemexpress LLC HY15244A200MG

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Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor. It demonstrates antineoplastic activity and effectively inhibits common PIK3CA somatic mutations.

  • Potent, orally active, and selective PI3Kα inhibitor
  • Effectively inhibits common PIK3CA somatic mutations
  • Potently inhibits Akt phosphorylation in PI3Kα-transformed cells
  • Induces G0/G1 phase cell cycle arrest in osteosarcoma cells
  • Significantly reduces tumor volumes in osteosarcoma animal models

Catalog No. 50-003-72414


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