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Medchemexpress LLC Alpelisib (hydrochloride) | 1584128-91-5 | C19H23ClF3N5O2S | 200 MG

Supplier: Medchemexpress LLC HY15244A200MG
Alpelisib hydrochloride is a potent, orally active, and selective PI3Kα inhibitor. It demonstrates antineoplastic activity and effectively inhibits common PIK3CA somatic mutations.
- Potent, orally active, and selective PI3Kα inhibitor
- Effectively inhibits common PIK3CA somatic mutations
- Potently inhibits Akt phosphorylation in PI3Kα-transformed cells
- Induces G0/G1 phase cell cycle arrest in osteosarcoma cells
- Significantly reduces tumor volumes in osteosarcoma animal models
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