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Medchemexpress LLC Alpha-Estradiol | 57-91-0 | MFCD00064144 | 99.5% | 1 G
Supplier: Medchemexpress LLC HYB0141A1G
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor. It is utilized as a topical medication for the treatment of androgenic alopecia and is classified as a human endogenous metabolite.
- Weak estrogen and 5 alpha-reductase inhibitor
- Inhibits testosterone metabolism catalyzed by 5 alpha-reductase
- Attenuates LPS-induced inflammatory markers in various cell types
- Decreases NFκB-p65 and increases ER alpha protein expression
- Reduces central avascular/total retina area in mouse models
- Decreases malondialdehyde (MDA) levels in hyperoxia-exposed pups
- Reduces NADPH-oxidase-positive cells, concentration, and activity in pup retinas
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