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Medchemexpress LLC Alphitolic acid | 19533-92-7 | 500 UG
Supplier: Medchemexpress LLC HYN2855500UG
Alphitolic acid is an anti-inflammatory triterpene found in Quercus aliena. It induces apoptosis by blocking Akt-NF-κB signaling and also induces autophagy. It exhibits anti-inflammatory activity by down-regulating NO and TNF-α production and is used for cancer and inflammation research.
- Anti-inflammatory activity
- Induces apoptosis by blocking Akt-NF-κB signaling
- Induces autophagy
- Down-regulates nitric oxide and TNF-α production
- Shows anti-proliferative activity in oral cancer cells
- Increases p53 phosphorylation and expression
- Decreases expression of the oncogenic E3 ligase MDM2
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