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Apexbio Technology LLC AMG 510(Synonyms: Sotorasib, Lumakras, AMG510, KRAS G12C inhibitor, AMG-510), 10mg, CAS: 2296729-00-3.
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Supplier:  Apexbio Technology LLC B839910

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AMG 510 (CAS 2296729-00-3) is an orally bioavailable selective covalent inhibitor targeting KRAS G12C Its mechanism involves binding KRAS G12C mutant protein and stabilizing it in an inactive GDP-bound conformation By preventing nucleotide exchange AMG 510 suppresses downstream signaling pathways linked to cellular proliferation and survival resulting in tumor regression in preclinical KRAS G12C-driven cancer models It serves as an important tool for biomedical research focused on RAS-driven oncogenic signaling and targeted cancer therapeutics development

Catalog No. 50-000-59961


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