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Cayman Chemical AmIlorIdehydrochlorIdehy 5g

Supplier: Cayman Chemical 144095 G
A potassium-sparing diuretic; an ENaC inhibitor (K0.5 = 2.6 µM); inhibits sodium transport from bovine kidney cortex membrane vesicles (IC50 = 0.4 µM); inhibits u-PA (Ki = 7 µM) and the cardiac Na+/H+-ATPase (IC50 = 83.8 µM); inhibits calcium currents mediated by TRPP3 (IC50 = 143 µM); reduces mean arterial pressure in spontaneously hypertensive rats at 30 mg/kg
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