Medchemexpress LLC Amino-PEG4-Val-Cit-PAB-MMAE | 1492056-71-9 | 99.9% | 1370.71 g/mol | C69H115N11O17 | 25 MG

Supplier:  Medchemexpress LLC HY14115425MG

Amino-PEG4-Val-Cit-PAB-MMAE is a cleavable 4-unit polyethylene glycol (PEG) linker containing a valine-citrulline (Val-Cit) dipeptide and a para-aminobenzyl (PAB) self-immolative spacer designed for use in antibody-drug conjugate (ADC) synthesis. It provides a hydrophilic spacer, a protease-cleavable linker for controlled payload release, and an amine handle for conjugation to payloads such as MMAE. Supplied as a purified solid for research use and soluble in DMSO.

• Cleavable Val-Cit dipeptide enables protease-mediated payload release.
• PAB self-immolative spacer enables rapid payload release after cleavage.
• Four-unit PEG spacer increases hydrophilicity and solubility.
• Primary amine handle supports site-specific conjugation chemistries.
• High purity and characterized molecular weight for reproducible conjugation.
• Soluble in DMSO at 100 mg/mL for convenient stock preparation.

Catalog No. 50-002-03789