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Cayman Chemical AmInoxyACtIc ACDhydrochl 250mg
SDP

Supplier:  Cayman Chemical 28298250 MG

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A GABA-T inhibitor (Ki = 9.16 μM) that induces GABA accumulation in the brain; inhibits CBS and CSE (IC50s = 8.5 and 1.1 μM, respectively); decreases GABA-T activity and increases GABA levels in all regions of rat brain at 100 mg/kg; decreases GABA-T activity and increases GABA in mouse brain at 13 mg/kg; inhibits 3-mercaptopropionic acid-, strychnine-, and pentetrazole-induced seizures in mice (ED50s = 53, 130, and 85 mg/kg, respectively); exhibits neurotoxicity in the chimney test (ED50 = 62 mg/kg) and is lethal (LD50 = 105 mg/kg) to mice

Catalog No. 50-294-0416


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