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Apexbio Technology LLC Amisulpride 71675-85-9 50mg
Supplier: Apexbio Technology LLC B147950
Amisulpride is a small-molecule antagonist targeting dopamine D2 and D3 receptor subtypes It is designed to inhibit dopamine-mediated receptor activation thereby modulating dopaminergic signaling pathways Amisulpride exerts its biological activity primarily through antagonism of dopamine receptors In radioligand binding assays using rat striatal D2 autoreceptors and limbic brain regions amisulpride demonstrates high binding affinity with Ki values of approximately 2 8 nM (D2) and 3 2 nM (D3) Additionally it inhibits dopamine agonist-induced cellular responses such as quinpirole-stimulated thymidine incorporation Based on these pharmacological properties amisulpride holds research potential in dopamine receptor-related neurochemical research and investigations of dopaminergic signaling pathways
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