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Abcam AMN082 dihydrochloride, mGlu7 agonist, 50MG

Supplier:  Abcam AB12001150MG

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MW 465.5 Da, Purity >98%. Potent, selective, orally active and brain penetrant mGlu7 receptor agonist. Potently inhibits cAMP accumulation and stimulates GTP binding (EC50 = 64-290 nM) in mGluR7 transfected cells. Selective over mGlu1, 2, 3, 4,5, 6, and 8, ionotropic receptors (up to 10 μM). Elevates plasma stress hormones *in vivo*. Induces mGlu7 receptor internalisation in dissociated hippocampal neurones.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-7943


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