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AdipoGen anti-Caspase-1 (p20) (mouse), mAb (Casper-1),Monoc
Supplier: AdipoGen AG20B0042C100
anti-Caspase-1 (p20) (mouse), mAb (Casper-1), AdipoGen Life Sciences. Monoclonal Antibody. Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Isotype: Mouse IgG1. Clone: Casper-1. Applications: IHC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
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