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ECM Bioscience Dok1 (Tyr-362)[Dok2 (Tyr-337)], phospho-specific Rabbit Polyclonal Antibody, ECM Biosciences

Supplier:  ECM Bioscience DP2241

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This antibody was cross-adsorbed to a phosphotyrosine peptide before affinity purification using phospho-Dok1 (Tyr-362) peptide. The purified antibody detects a band at 62 kDa* corresponding to Dok1 in western blots of human Jurkat cells, but does not detect this band after alkaline phosphatase treatment. Similar to Dok1 (Ser-450) antibody, this antibody also detects an 80 kDa band that has not been identified. The immunogen was Phospho-Dok1 (Tyr-362) synthetic peptide (coupled to KLH) corresponds to amino acids surrounding tyrosine 362 in human Dok1. This sequence is conserved in Dok1 from rat and mouse (Tyr-361), and has high homology to Dok2 (Tyr-337). The site is not conserved in other Dok family members. Accession #Q99704. Applications = WB, E; Species Reactivity = Hu, Rt, Ms; Size = 100 μl; Buffer = PBS, 50% glycerol, 1 mg/ml BSA, and 0.05% sodium azide. Store at –20°C. Stable for 1 year. Other Names = p62DOK

Catalog No. 50-206-8693


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