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Sigma Aldrich Fine Chemicals Biosciences Anti-E6AP antibody, Mouse monoclonal | MFCD04034520 | 200uL
Supplier: Sigma Aldrich Fine Chemicals Biosciences E8655200UL

E6AP is an E3 ubiquitin ligase that is expressed by the UB3A gene. Inhibiton or alterations of the UB3A gene may cause a neurological disorder called the Angelman Syndrome. E6AP interacts with E1 and E2 enzymes to mediate ubiquitination of proteins marked for degradation. E6AP also binds with the E6 viral protein present in HPV-infected cells. Monoclonal Anti-E6AP antibody is a useful tool for the study of E6AP and its function in protein degradation. This antibody is specific for E6AP protein in rat, mouse, human and monkey.
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