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Bio X Cell InVivoMAb Anti-Human CD3, Clone OKT-3, Mouse IgG2a, 0.2 μm Filtered
Supplier: Bio X Cell BE00012R025MG
The InVivoMAb anti-human CD3 antibody, clone OKT-3, targets human CD3ε, a 20 kDa transmembrane protein integral to the TCR complex. Found on T lymphocytes, NK-T cells, and developing thymocytes, CD3ε is vital for TCR signaling, T cell activation, and antigen recognition. This antibody possesses in vivo immunosuppressive properties and effectively treats allograft rejection.
- Reacts with human CD3ε
- Used for in vitro T cell stimulation/activation
- Applicable for in vivo T cell depletion in humanized mice
- Facilitates ex vivo T cell inhibition for xenografts
- Suitable for flow cytometry
- Formulated in PBS, pH 7.0, without stabilizers or preservatives
- Endotoxin level is ≤1EU/mg
- Purity is ≥95%
- Sterilized by 0.2 μm filtration
- Produced in an animal-free facility
- Purified using protein G
- Store at 4°C; do not freeze
- Has a molecular weight of 150 kDa
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