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STEMCELL Technologies Anti-Human Nestin Antibody, Clone 10C2, Alexa Fluor 488, Size: 25 µg
Supplier: STEMCELL Technologies 60091AD.1
Clone 10C2 is a mouse monoclonal antibody that reacts with human and cynomolgus nestin, a class VI intermediate filament (IF) protein expressed by embryonic neuroepithelial stem cells in the developing nervous system and by pancreatic islet and mesenchymal progenitor cells. Verified for use with flow cytometry, immunocytochemistry, immunofluorescence microscopy, and western blotting assays, use this antibody in applications requiring the detection of nestin. Nestin expression is also observed in glioblastomas and many primary and metastatic melanomas and it is a useful angiogenic marker to evaluate neovascularity of endothelial cells in tumors. The 10C2 antibody reportedly cross-reacts weakly with monkey nestin but not rodent nestin. A doublet band of ~220 - 250 kDa is observed on western blots with this antibody. Visit STEMCELL.com for more information and related products.
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