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Bio X Cell Anti-Mouse CTLA-4 (CD152) Antibody, Clone 9H10, Syrian Hamster IgG, Unconjugated
Supplier: Bio X Cell BE0131R050MG
The 9H10 monoclonal antibody targets mouse CTLA-4 (CD152), a 33 kDa cell surface receptor on activated T and B lymphocytes. This antibody negatively regulates cell-mediated immune responses, crucial for immunological tolerance and protective immunity, by blocking CTLA-4 binding to B7 co-receptors to promote T cell co-stimulation.
- Isotype: Syrian hamster IgG
- Immunogen: Mouse CTLA-4-human IgG1 fusion protein
- Applications: in vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Western blot
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1 EU/mg
- Purity: ≥95% (SDS-PAGE)
- Sterility: 0.2 μm filtration
- Production: Animal-free facility, Protein G purification
- Molecular weight: 150 kDa
- Storage: 4°C; do not freeze
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