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Bio X Cell Anti-Mouse CTLA-4 (CD152) Antibody, Clone 9H10, Syrian Hamster IgG, Unconjugated

Supplier:  Bio X Cell BE0131R050MG

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The 9H10 monoclonal antibody targets mouse CTLA-4 (CD152), a 33 kDa cell surface receptor on activated T and B lymphocytes. This antibody negatively regulates cell-mediated immune responses, crucial for immunological tolerance and protective immunity, by blocking CTLA-4 binding to B7 co-receptors to promote T cell co-stimulation.

  • Isotype: Syrian hamster IgG
  • Immunogen: Mouse CTLA-4-human IgG1 fusion protein
  • Applications: in vivo CTLA-4 neutralization, in vitro CTLA-4 neutralization, Western blot
  • Formulation: PBS, pH 7.0, no stabilizers or preservatives
  • Endotoxin: ≤1 EU/mg
  • Purity: ≥95% (SDS-PAGE)
  • Sterility: 0.2 μm filtration
  • Production: Animal-free facility, Protein G purification
  • Molecular weight: 150 kDa
  • Storage: 4°C; do not freeze

Catalog No. 50-562-413


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