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Bio X Cell InVivoMAb Anti-Mouse CD8 Alpha Antibody, 100 MG
Supplier: Bio X Cell BE0061R100MG
The 2.43 monoclonal antibody reacts with mouse CD8α, a transmembrane glycoprotein co-receptor for the T cell receptor (TCR). CD8α binds to class I MHC molecules on antigen-presenting cells (APC) and is expressed on cytotoxic T cells, thymocytes, natural killer cells, and some dendritic cell subsets. This antibody exhibits depleting activity when used in vivo.
- Isotype: Rat IgG2b, κ
- Conjugation: Unconjugated
- Immunogen: Mouse CTL clone L3
- Reported applications: in vivo CD8+ T cell depletion, Western blot
- Formulation: PBS, pH 7.0
- Endotoxin: ≤1 EU/mg by LAL assay
- Purity: ≥95% (SDS-PAGE)
- Sterility: 0.2 µm filtration
- Production: Animal-free purified
- Purification: Protein G
- Molecular weight: 150 kDa
- Storage: Store at stock concentration at 4°C. Do not freeze.
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