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Leinco Technologies Inc Anti-Mouse CD209b (SIGN-R1, DC-SIGNR1) In Vivo GOLD; Clone 22D1; Isotype: Armenian Hamster IgG1 κ
Supplier: Leinco Technologies Inc C285950 MG
Specificity: Clone 22D1 recognizes an epitope on mouse CD209b. Antigen Distribution: CD209b is predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. Background: CD209b has a predicted molecular weight of 37 kD and is a single-pass type II membrane protein containing a C-type lectin domain. CD209b plays a role in innate immune response, mediating the recognition and uptake of pathogen products such as lipopolysaccharides, pneumococcal polysaccharides, and dextrans. CD209b is a mouse homolog of human CD209. Applications: (IHC (Frozen), FC, WB, B) Leinco’s In vivo GOLDTM and In vivo PLATINUMTM functional antibodies are manufactured in an animal free facility using only In vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
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